In delivering health care, effective teamwork can immediately and positively affect patient safety and outcome. The evolution in health care and global demand for quality patient care necessitates parallel health care professional development with a great focus on a patient-centered teamwork approach. This can only be achieved by placing the patient in the center of care and through sharing a wide-based culture of values and principles. This will help form and develop an effective team able to deliver exceptional care to the patients. Aiming toward this goal, the motivation of team members should be backed by strategies and practical skills to achieve goals and overcome challenges.